wsabi

Precision Locus Targeting

Configuration

1. Target Locus Source

Chr:Pos

2. Variant Data

📂

Drag & drop or click to browse

VCF · TSV · JSON

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3. Filters Rare Variants Only (MAF < 5%) Coding Regions Only

Sequence Padding (bp)

Results

Waiting for input...

Upload a file and define a target to see results.

Configuration

Target Locus

Chr:Pos

Methylation Data

🧬

Drag & drop or click to browse

TSV · TSV.GZ

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Sequence Padding (bp)

Results

Waiting for input...

Upload data and run analysis

Action Completed

Ready

Download Reference Data

Access our curated collection of SNP datasets, reference genomes, and annotation files.

📂

wsabi Data Repository

Hosted on SharePoint

Access Repository ↗

🌐 Free Access & Open Data

All datasets available through wsabi are publicly accessible and free to use. We are committed to providing researchers with open access to genomic data.

💻 GitHub: https://github.com/andrearossi-lab

v4.0 Current

🎉 Methylation Analysis Support

Methylation Analysis Tab - Complete tabbed interface for SNP and Methylation workflows
Genome-wide methylation data - Full support for KOLF2.1J PacBio long-read methylation datasets (.tsv.gz)
All 4 locus modes available - Coordinates, gRNA Cut Site, Gene Name, Gene + gRNA Sequence
Enhanced methylation display - Probability visualization, methylated base (C/G) with strand (+/-)
Clinical annotations - ClinVar integration and MAF data for methylation sites
Side-by-side layout - Configuration and results panels displayed horizontally
Smart file parsing - Automatic gzip decompression with pako library
Bug fixes - Fixed .tsv.gz parsing freeze, chromosome format normalization, API integration

📊 Available Datasets

WTC-11 SNP datasets - Comprehensive SNP variant data from WTC-11 cell line (Illumina)
KOLF2.1J SNP datasets - Comprehensive SNP variant data from KOLF2.1J cell line (Illumina, PacBio and ONT)
iPS12 SNP datasets - Comprehensive SNP variant data from iPS12 cell line (ONT)
KOLF2.1J Methylation - PacBio long-read methylation genome-wide data
VCF/TSV/JSON formats supported

v3.0

Initial SNP analysis release
VCF/TSV/JSON file support
Gene lookup and gRNA sequence mapping
Clinical significance and MAF integration
Genomic context visualization

Configuration

Results

Configuration

Results

Info & Datasets

Download Reference Data

wsabi Data Repository

🎉 Methylation Analysis Support

📊 Available Datasets